Sujin Lee
Division of Applied Life Science (Brain Korea 21), Gyeongsang National University, Jinju, Republic of Korea
Jinju-si, Kyongsang-namdo, Republic of Korea
Hyein Park
Department of Systems Biology, Division of Life Sciences, Institute for Life Science and Biotechnology, Yonsei University
Seodaemun-gu, Kyongsang-namdo, Republic of Korea
Boyoung Lee
Department of Systems Biology, Division of Life Sciences, and Institute for Life Science and Biotechnology, Yonsei University
Seoul, Seoul-t'ukpyolsi, Republic of Korea
Jaehyo Park
Department of Systems Biology, Division of Life Sciences, and Institute for Life Science and Biotechnology, Yonsei University
Seoul, Seoul-t'ukpyolsi, Republic of Korea
Ju Yeon Song
Department of Systems Biology, Division of Life Sciences, and Institute for Life Science and Biotechnology, Yonsei University
Seoul, Seoul-t'ukpyolsi, Republic of Korea
Soon-kyeong Kwon
Division of Applied Life Science (Brain Korea 21), Gyeongsang National University, Jinju, Republic of Korea
Jinju-si, Kyongsang-namdo, Republic of Korea
Jihyun F. Kim
Department of Systems Biology, Division of Life Sciences, and Institute for Life Science and Biotechnology, Yonsei University
Seoul, Seoul-t'ukpyolsi, Republic of Korea
The soil-borne pathogen Ralstonia solanacearum causes bacterial wilt and thereby crop losses in the Solanaceae plants including tomato, potato, pepper, and eggplant. Although the susceptibility to the wilt disease primarily depends on the plant genotype, the microbial community in the rhizosphere also contributes to the severity. A flavobacterium TRM1, isolated from the wilt-resistant tomato cultivar Hawaii 7996, suppresses Ralstonia wilt in a susceptible tomato cultivar. The antagonistic activity of TRM1 against R. solanacearum was also observed from co-cultivation of the two bacteria in mCPG medium. To infer the wilt-suppressing mechanism, a large-scale transcriptional characterization was conducted. The transcriptional changes of TRM1 and R. solanacearum under the co-cultivation condition were compared to those in mono-cultivation. The transcriptome data of TRM1, R. solanacearum, and tomato were also collected in the plant rhizosphere. Genes for several secretion systems in R. solanacearum were inferred to be associated with virulence, while genes encoding some membrane-bound proteins in TRM1 appeared to be associated with virulence suppression. Integrating the results of these transcriptional data helped us systematically understand the wilt-suppressing mechanisms between the plant pathogen, the disease-suppressing microbe, and the host plant.